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Two Steps, One System: RY-NSG Series Combines Extraction and Concentration in a Single Compact Skid

Time: 2026-03-23

Look at a typical botanical extraction floor and you'll see the problem immediately: an extraction tank here, a pipe bridge snaking across the ceiling, a single-effect concentrator tucked in the corner, and a maze of transfer lines connecting them all. Every flange is a leak point. Every pump is a residence-time variable. Every meter of uninsulated transfer pipe is energy bleeding into the air. And when you're processing heat-sensitive actives — polyphenols, flavonoids, alkaloids — that thermal exposure between unit operations silently kills your yield.

The RY-NSG Series eliminates the gap. It integrates extraction and vacuum concentration into a single closed-loop skid, so your actives never travel, never cool down, and never degrade between steps.

The Hidden Cost of Separate Units

When extraction and concentration are decoupled, three things happen:

  1. Thermal loss — extract liquor cools during transfer, forcing the concentrator to re-heat it. Double the energy, double the thermal degradation.
  2. Oxidation exposure — polyphenols and unsaturated compounds oxidize at every transfer point, reducing active content and darkening the product.
  3. Solvent inventory — between tanks, pipes, and hold vessels, you're carrying 20–40% more solvent volume than your batch size requires, inflating recovery costs.

The RY-NSG Series addresses all three by keeping the process contained from raw material loading to concentrated extract discharge.

RY-NSG Series: How It Works

Step 1 — Dynamic Extraction

Material is loaded into the jacketed extraction vessel. Solvent (water, ethanol, or mixed) is circulated through the bed by a high-flow pump, maintaining turbulent contact between solvent and solids. Temperature is controlled via the jacket and an in-line heat exchanger with ±1°C precision. Extraction time, temperature, and circulation rate are all programmable.

Step 2 — Direct Vacuum Concentration

Without transferring the extract, the system transitions to concentration mode. The same vessel now operates under controlled vacuum (down to -0.095 MPa), lowering the boiling point to 40–60°C. Solvent vapor rises, is condensed in a shell-and-tube condenser, and is collected in a separate recovery tank. The concentrated extract remains in the vessel — no transfer, no intermediate hold time, no oxidation window.

Integrated Features

Feature Benefit
Jacketed extraction + external circulation Uniform temperature, no hot spots, faster mass transfer
Vacuum concentration down to 40°C Preserves heat-sensitive actives; no caramelization
Solvent recovery ≥ 95% Cuts operating cost; ethanol reuse cycle in a closed loop
CIP spray ball included Clean-in-place between batches — < 30 minutes turnaround
316L contact surfaces FDA / GMP compliant for food, pharmaceutical, and cosmetic extracts

Configurations That Fit Your Lab and Pilot Needs

Model Extraction Volume Concentration Rate Best For
RY-NSG-10 10 L 3–5 L/h Academic research, natural product chemistry
RY-NSG-30 30 L 8–12 L/h Formulation development, small-batch production
RY-NSG-50 50 L 15–25 L/h Pilot validation, clinical trial material
RY-NSG-100 100 L 30–50 L/h Pilot production, process economic verification

All models share identical geometry, heat-transfer surface-to-volume ratios, and control architecture — so parameters established on the RY-NSG-10 transfer directly to the RY-NSG-100 and beyond.

What Customers Are Running

Feedstock Active Target Process Advantage
Green tea leaves Polyphenols (EGCG) Low-temp concentration prevents epimerization
Turmeric rhizome Curcuminoids Ethanol circulation maximizes yield at < 60°C
Ginseng root Ginsenosides Combined water/ethanol gradient extraction in a single batch
Mushroom fruiting bodies Polysaccharides (beta-glucans) Hot water extraction followed by low-vacuum concentration — no browning
Citrus peel Flavonoids, essential oils

Volatile fraction trapped in solvent recovery loop

The System That Connects the Chain

The RY-NSG Series doesn't stop at the concentrate. The saturated extract exits ready for downstream processing through RY-1500spray dryersvacuum belt dryers, or lyophilizers — forming a seamless Raw Material → Extract → Dry Powder pipeline.

For laboratories, it replaces a bench full of disconnected glassware. For pilot plants, it replaces two standalone vessels, a transfer pump, and the engineering time you spend chasing temperature drops.

The fewer times your extract touches air, the better it works. The RY-NSG Series keeps it to one.


Download the RY-NSG Series datasheet and application notes, or speak with our extraction technology team about your specific feedstock.

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